The collaborators described in this proposal are all well established in this field and therefore bring substantial existing infrastructure, expertise, and funds to this project. However, the Governance Group and the other collaborators understand that further independent funding will be necessary to sustain and expand this effort both at each site and as a community. The combination of existing infrastructure, critical start-up funds, and longer term sustaining funds, will enable continuation of a project that will more likely grow well beyond the initial aims described here.